🧬 Peptide Profile
Compound
Semaglutide
CAS Number
910463-68-2
Molecular Formula
C₁₈₇H₂₉₁N₄₅O₅₉ (structure-dependent)
Molecular Weight
~4113.6 g/mol
Sequence
Modified GLP-1 analogue peptide with structural modifications
Purity
≥99% (HPLC)
Form
Lyophilised peptide (solid cake)
Appearance
White to off-white lyophilised solid
🧪 Usage & Storage
Intended Use
Semaglutide is a synthetic peptide supplied for laboratory research applications, including biochemical and analytical studies.
Storage
Store lyophilised peptide at 2–8°C (refrigerated)
For extended stability, storage at -20°C is recommended
Keep vial tightly sealed and protected from moisture and light
Avoid repeated freeze-thaw cycles where possible
For detailed guidance on reconstitution and handling, please refer to our reconstitution and storage guidelines blog.
🧪 Synthesis & Quality Assurance
Synthesis Overview
Semaglutide is produced using solid-phase peptide synthesis (SPPS), enabling controlled assembly of the peptide sequence with high fidelity.
Modification
Post-synthesis, structural modifications are applied to enhance stability and functional characteristics.
Purification
The material is purified via high-performance liquid chromatography (HPLC) to remove impurities and truncated sequences.
Lyophilisation
The purified peptide is lyophilised (freeze-dried) to yield a stable solid form suitable for storage.
Analytical Characterisation
Each batch is analysed using:
HPLC for purity assessment
Mass spectrometry (MS) for molecular weight confirmation
Quality Assurance
Batches are produced under controlled laboratory conditions and evaluated against predefined quality criteria to ensure consistency, identity, and purity.
Batch Consistency
Standardised processes and analytical verification ensure reproducibility across production batches.
Further Information
For additional detail on peptide synthesis processes, please refer to our “How Peptides Are Made” blog.
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